Cavernous angiomas: An uncontrolled clinical study of 87 surgically treated patients

作者: Giedrimantas Bernotas , Daiva Rastenytė , Vytenis Deltuva , Algis Matukevičius , Vanda Jaškevičienė

DOI: 10.3390/MEDICINA45010004

关键词:

摘要: Background. Cerebral cavernous angiomas remain as one of the most negotiable and controversial topics in neurological neurosurgical practice. We present statistical evaluation initial presentation, preoperative findings, surgical complications, outcome surgically treated patients with intracerebral angiomas. Methods. During 1997 to 2004, 87 (41 men, 46 women) underwent treatment tertiary referral center, these were included into uncontrolled clinical study. The mean age at time operation was 42.4 years, duration illness 120.5 days. All magnetic resonance imaging, pre- postoperative examination. course documented using Karnofski performance scale. A simplified version Engel’s classification chronic seizures applied. Results. common presentation seizures, significant part which chronic. No association found between lesion location by cerebral lobes seizures. differences likelihood presenting hemorrhage supratentorial subtentorial lesions detected. In addition, no associations size cavernoma an extralesional or group headache, sporadic hemorrhage, good achieved 83% patients. Of who for seizure control, reduction elimination after surgery observed 79% Conclusions. Microsurgical removal surrounding hemosiderin plate tends epileptic improved status.

参考文章(25)
I Requena, M Arias, L Lopez-Ibor, I Pereiro, A Barba, A Alonso, E Monton, Cavernomas of the central nervous system: clinical and neuroimaging manifestations in 47 patients. Journal of Neurology, Neurosurgery & Psychiatry. ,vol. 54, pp. 590- 594 ,(1991) , 10.1136/JNNP.54.7.590
C. Mottolese, M. Hermier, H. Stan, A. Jouvet, G. Saint-Pierre, J.-C. Froment, P. Bret, C. Lapras, Central nervous system cavernomas in the pediatric age group. Neurosurgical Review. ,vol. 24, pp. 55- 73 ,(2001) , 10.1007/PL00014581
Barbara G. Vickrey, Ron D. Hays, Jerome Engel, Karen Spritzer, William H. Rogers, Rebecca Rausch, Jason Graber, Robert H. Brook, Outcome assessment for epilepsy surgery: the impact of measuring health-related quality of life. Annals of Neurology. ,vol. 37, pp. 158- 166 ,(1995) , 10.1002/ANA.410370205
John R. Robinson, Issam A. Awad, Michele Magdinec, Lata Paranandi, Factors predisposing to clinical disability in patients with cavernous malformations of the brain. Neurosurgery. ,vol. 32, pp. 730- 736 ,(1993) , 10.1227/00006123-199305000-00005
Paolo Cappabianca, A. Alfieri, F. Maiuri, G. Mariniello, S. Cirillo, E. de Divitiis, Supratentorial cavernous malformations and epilepsy: seizure outcome after lesionectomy on a series of 35 patients☆ Clinical Neurology and Neurosurgery. ,vol. 99, pp. 179- 183 ,(1997) , 10.1016/S0303-8467(97)00023-1
John L. Moriarity, Matthew Wetzel, Richard E. Clatterbuck, Sam Javedan, Jeannie-Marie Sheppard, Karen Hoenig-Rigamonti, Nathan E. Crone, Steven N. Breiter, Roland R. Lee, Daniele Rigamonti, The Natural History of Cavernous Malformations: A Prospective Study of 68 Patients Neurosurgery. ,vol. 44, pp. 1166- 1173 ,(1999) , 10.1097/00006123-199906000-00003
Toyotaka Aiba, Ryuichi Tanaka, Tetsuo Koike, Shigeki Kameyama, Norio Takeda, Tadashi Komata, Natural history of intracranial cavernous malformations Journal of Neurosurgery. ,vol. 83, pp. 56- 59 ,(1995) , 10.3171/JNS.1995.83.1.0056
J. Nozipo Maraire, Issam A. Awad, Intracranial cavernous malformations: lesion behavior and management strategies. Neurosurgery. ,vol. 37, pp. 591- 605 ,(1995) , 10.1227/00006123-199510000-00001
MJ Hennessy, RDC Elwes, M Honavar, S Rabe-Hesketh, CD Binnie, CE Polkey, Predictors of outcome and pathological considerations in the surgical treatment of intractable epilepsy associated with temporal lobe lesions Journal of Neurology, Neurosurgery & Psychiatry. ,vol. 70, pp. 450- 458 ,(2001) , 10.1136/JNNP.70.4.450
Henry W.S. Schroeder, Michael R. Gaab, U. Runge, Supratentorial Cavernous Angiomas and Epileptic Seizures: Preoperative Course and Postoperative Outcome Neurosurgery. ,vol. 39, pp. 1271- 1271 ,(1996) , 10.1097/00006123-199612000-00058