MiR-451 antagonist protects against cardiac fibrosis in streptozotocin-induced diabetic mouse heart.

作者: Cui Liang , Lu Gao , Yuan Liu , Yuzhou Liu , Rui Yao

DOI: 10.1016/J.LFS.2019.02.059

关键词:

摘要: … Activation of AMPKa1/mTOR was decreased in diabetic mouse heart tissue and hyperglycemia-stimulated MHECs, which was increased following miR-451 knockdown or inhibition. …

参考文章(32)
Lei Song, Ming Su, Shuiyun Wang, Yubao Zou, Xiaojian Wang, Yilu Wang, Hongli Cui, Peng Zhao, Rutai Hui, Jizheng Wang, MiR-451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC1. Journal of Cellular and Molecular Medicine. ,vol. 18, pp. 2266- 2274 ,(2014) , 10.1111/JCMM.12380
Qing-Qing Wu, Man Xu, Yuan Yuan, Fang-Fang Li, Zheng Yang, Yuan Liu, Meng-Qiao Zhou, Zhou-Yan Bian, Wei Deng, Lu Gao, Hongliang Li, Qi-Zhu Tang, Cathepsin B deficiency attenuates cardiac remodeling in response to pressure overload via TNF-α/ASK1/JNK pathway American Journal of Physiology-heart and Circulatory Physiology. ,vol. 308, ,(2015) , 10.1152/AJPHEART.00601.2014
Zhonghan Li, Tariq M. Rana, Therapeutic targeting of microRNAs: current status and future challenges Nature Reviews Drug Discovery. ,vol. 13, pp. 622- 638 ,(2014) , 10.1038/NRD4359
Shali Chen, Terry Evans, Kallol Mukherjee, Morris Karmazyn, Subrata Chakrabarti, Diabetes-induced myocardial structural changes: role of endothelin-1 and its receptors. Journal of Molecular and Cellular Cardiology. ,vol. 32, pp. 1621- 1629 ,(2000) , 10.1006/JMCC.2000.1197
Hilah Gal, Gopal Pandi, Andrew A. Kanner, Zvi Ram, Gila Lithwick-Yanai, Ninette Amariglio, Gideon Rechavi, David Givol, MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells. Biochemical and Biophysical Research Communications. ,vol. 376, pp. 86- 90 ,(2008) , 10.1016/J.BBRC.2008.08.107
Beate Fisslthaler, Ingrid Fleming, Activation and Signaling by the AMP-Activated Protein Kinase in Endothelial Cells Circulation Research. ,vol. 105, pp. 114- 127 ,(2009) , 10.1161/CIRCRESAHA.109.201590
Denise Hileeto, Mark Cukiernik, Suranjana Mukherjee, Terry Evans, Yousef Barbin, Donal Downey, Morris Karmazyn, Subrata Chakrabarti, Contributions of endothelin-1 and sodium hydrogen exchanger-1 in the diabetic myocardium Diabetes-metabolism Research and Reviews. ,vol. 18, pp. 386- 394 ,(2002) , 10.1002/DMRR.322
Yasuhide Kuwabara, Takahiro Horie, Osamu Baba, Shin Watanabe, Masataka Nishiga, Shunsuke Usami, Masayasu Izuhara, Tetsushi Nakao, Tomohiro Nishino, Kinya Otsu, Toru Kita, Takeshi Kimura, Koh Ono, MicroRNA-451 Exacerbates Lipotoxicity in Cardiac Myocytes and High-Fat Diet-Induced Cardiac Hypertrophy in Mice Through Suppression of the LKB1/AMPK Pathway Circulation Research. ,vol. 116, pp. 279- 288 ,(2015) , 10.1161/CIRCRESAHA.116.304707
Janet K. Lighthouse, Eric M. Small, Transcriptional control of cardiac fibroblast plasticity Journal of Molecular and Cellular Cardiology. ,vol. 91, pp. 52- 60 ,(2016) , 10.1016/J.YJMCC.2015.12.016
Ilaria Russo, Nikolaos G. Frangogiannis, Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities Journal of Molecular and Cellular Cardiology. ,vol. 90, pp. 84- 93 ,(2016) , 10.1016/J.YJMCC.2015.12.011