High susceptibility of Djungarian hamsters (Phodopus sungorus) to the infection with Babesia microti supported by hemodynamics.

摘要: As the comparative study was carried out on susceptibility by pursuit of parasitemia among Djungarian, Syrian, and Chinese hamsters as well BALB/c mice infected with Syrian hamster-adapted Babesia microti strain, Djungarian showed highest them. Then, other hematological parameters were pursued in B. strain. Remarkable symptoms observed hemoglobinuria clinically, anemia hematologically, splenomegaly macroscopically during all over observation period for 24 weeks post infection (PI). Parasitemia began to rise at 2 peaked 4 PI. After that, decreased gradually but maintained a level about 10% average until PI end experiment. A decrease RBC count, Hb, PCV, an increase reticulocyte WBC counts due development immature neutrophils, lymphocytes monocytes recognized together parasitemia. The had macrocytic hypochromic MCV MCHC growth phase parasite. It considered that will be useful examination, isolation, maintenance, passage laboratory.