CRISPR/Cas9-mediated simultaneous knockout of Dmrt1 and Dmrt3 does not recapitulate the 46,XY gonadal dysgenesis observed in 9p24.3 deletion patients

作者: Masafumi Inui , Moe Tamano , Tomoko Kato , Shuji Takada

DOI: 10.1016/J.BBREP.2017.01.001

关键词:

摘要: … only several exons of the DMRT1 gene or regulatory variants of DMRT1 are found in … Dmrt1 locus (Dmrt1 1ins ; Dmrt3 WT ), Dmrt3 locus (Dmrt1 WT ; Dmrt3 8del ) and both loci (Dmrt1 …

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