Why buprenorphine is so successful in treating opiate addiction in France

作者: M. Fatseas , Marc Auriacombe

DOI: 10.1007/S11920-007-0046-2

关键词:

摘要: In France, all registered medical doctors have been allowed to prescribe buprenorphine without any special education or licensing since 1995. This has led a rapidly increasing number of opiate-dependent users under treatment in primary care. French physician compensation mechanisms, pharmacy services, and insurance funding contributed minimizing barriers treatment. Approximately 20% physicians France are prescribing treat more than one half the estimated 180,000 problem heroin users. Intravenous diversion may occur up patients relatively rare overdoses combination with sedatives, whereas total opiate overdose deaths declined substantially. maintenance for was feasible safe through office-based prescriptions relaxed regulatory environment.

参考文章(44)
Comparison of buprenorphine and methadone in the treatment of opioid dependence American Journal of Psychiatry. ,vol. 151, pp. 1025- 1030 ,(1994) , 10.1176/AJP.151.7.1025
Isabelle Feroni, Patrick Peretti-Watel, Alain Paraponaris, Alain Masut, Eleonore Ronfle, Jean-Claude Mabriez, Jean-Claude Mabriez, French general practitioners' attitudes and prescription patterns toward buprenorphine maintenance treatment: does doctor shopping reflect buprenorphine misuse? Journal of Addictive Diseases. ,vol. 24, pp. 7- 22 ,(2005) , 10.1300/J069V24N03_02
Yohann Perdrieux, Juan Menares, Sibel Bilal, Abdalla Toufik, Patrick De La Selle, Impact des traitements de substitution aux opiacés sur la vie sociale Elsevier Masson. ,(2008)
Jonathan E. Fielding, Lessons From France—'Vive la Différence' JAMA. ,vol. 270, pp. 748- 756 ,(1993) , 10.1001/JAMA.1993.03510060094040
Michael Soyka, Sabine M. Apelt, Martin Lieb, Hans-Ulrich Wittchen, One-year mortality rates of patients receiving methadone and buprenorphine maintenance therapy: a nationally representative cohort study in 2694 patients. Journal of Clinical Psychopharmacology. ,vol. 26, pp. 657- 660 ,(2006) , 10.1097/01.JCP.0000245561.99036.49
Michel Reynaud, Georges Petit, Denis Potard, Pascal Courty, Six deaths linked to concomitant use of buprenorphine and benzodiazepines Addiction. ,vol. 93, pp. 1385- 1392 ,(1998) , 10.1046/J.1360-0443.1998.93913859.X
J.P. Moatti, D. Vlahov, I. Feroni, V. Perrin, Y. Obadia, Multiple access to sterile syringes for injection drug users: vending machines, needle exchange programs and legal pharmacy sales in Marseille, France. European Addiction Research. ,vol. 7, pp. 40- 45 ,(2001) , 10.1159/000050713
Gwenaëlle Vidal-Trecan, Isabelle Varescon, Norbert Nabet, Alain Boissonnas, Intravenous use of prescribed sublingual buprenorphine tablets by drug users receiving maintenance therapy in France. Drug and Alcohol Dependence. ,vol. 69, pp. 175- 181 ,(2003) , 10.1016/S0376-8716(02)00312-5
X. Thirion, V. Lapierre, J. Micallef, E. Ronflé, A. Masut, V. Pradel, C. Coudert, J.C. Mabriez, J.L. Sanmarco, Buprenorphine prescription by general practitioners in a French region. Drug and Alcohol Dependence. ,vol. 65, pp. 197- 204 ,(2002) , 10.1016/S0376-8716(01)00161-2
T. Blanchon, A. Boissonnas, I. Varescon, G. Vidal-Trecan, Homelessness and High-Dosage Buprenorphine Misuse Substance Use & Misuse. ,vol. 38, pp. 429- 442 ,(2003) , 10.1081/JA-120017380