Osteo-Articular Infections in Newborns: Diagnosis and Treatment

作者: A. Dessì , M. Crisafulli , S. Accossu , V. Setzu , V. Fanos

DOI: 10.1179/JOC.2008.20.5.542

关键词:

摘要: AbstractOsteoarticular infections, although uncommon, represent a severe condition in neonates. Infections newborns are largely of an acute nature, transmitted by hematogenous means. The most frequently observed etiological agents are: Staphylococcus aureus, Gram negative and group B Streptococcus spp. In the majority acases metaphyses long bone commonly implicated sites, infection may spread to contiguous epiphysis joint Diagnosis septic arthritis osteomyelitis be hindered, especially neonates, due manifestation less clear-cut characteristic symptoms signs compared children. When is suspected, imaging techniques used association with blood tissue cultures reliable diagnostic tests. Antimicrobial treatment should administered for 3-4 weeks, initially intravenously, later switching oral medication. Surgery indicated drain abscesses or when no improvement is...

参考文章(47)
Luan Yin Chang, Tzou Yien Lin, Cheng Hsun Chiu, Feng Chen Kao, Zhon Liau Lee, Pei Wen Chung, Hui Chin Kao, Yhu Chering Huang, Acute hematogenous osteomyelitis and septic arthritis in children. Journal of Microbiology Immunology and Infection. ,vol. 36, pp. 260- 265 ,(2003)
Yao Jong Yang, Ching Chuan Liu, Shih Min Wang, Ching Hsiang Tsai, Chun Lung Wang, Septic arthritis in children: relationship of causative pathogens, complications, and outcome. Journal of Microbiology Immunology and Infection. ,vol. 36, pp. 41- 46 ,(2003)
Marrero Calvo M, Elvira Pardilla A, Iglesias Escalera G, Carpintero Martín I, Merino Arribas J, Ansó Oliván S, [Acute osteomyelitis. Clinical, radiological and bacteriological features and outcome]. Anales Espanoles De Pediatria. ,vol. 55, pp. 20- ,(2001)
Antonia Manoura, Sofia Maraki, Eftichia Korakaki, Christina Giannakopoulou, Emmanuel Velivasakis, Agisilaos Aligizakis, Emmanuel Saitakis, Eleftheria Hatzidaki, Maria Anatoliotaki, Methicillin-resistant Staphylococcus aureus osteomyelitis and septic arthritis in neonates: diagnosis and management. Japanese Journal of Infectious Diseases. ,vol. 60, pp. 129- 131 ,(2007)
David H. Smith, Arnold L. Smith, Eleanor D. Weissberg, Clinical features of neonatal osteomyelitis. Pediatrics. ,vol. 53, pp. 505- 510 ,(1974)
Gerald A. Mandell, Imaging in the diagnosis of musculoskeletal infections in children. Current Problems in Pediatrics. ,vol. 26, pp. 218- 237 ,(1996) , 10.1016/S0045-9380(06)80060-5
Avinash K. Shetty, Abraham Gedalia, Management of septic arthritis The Indian Journal of Pediatrics. ,vol. 71, pp. 819- 824 ,(2004) , 10.1007/BF02730722
Gerhardt Steinwender, Günter Schimpl, Birgit Sixl, Heimo H Wenzl, Gut-derived bone infection in the neonatal rat. Pediatric Research. ,vol. 50, pp. 767- 771 ,(2001) , 10.1203/00006450-200112000-00023
MB Vinod, J Matussek, N Curtis, HK Graham, JR Carapetis, Duration of antibiotics in children with osteomyelitis and septic arthritis. Journal of Paediatrics and Child Health. ,vol. 38, pp. 363- 367 ,(2002) , 10.1046/J.1440-1754.2002.00007.X