Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold

作者: Andrew D. Hamilton , Yoshitomo Hamuro

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摘要: A synthetic antibody mimic comprising multiple peptide loops built on an organic or molecular scaffold. In a highly preferred embodiment of the invention, calixarene unit comprises scaffold to which is attached plurality loops. The mimics allow for generation large libraries artificial antibodies that can be screened binding target antigens.

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