Amino acid composition of proteins: Selection against the genetic code.
作者： T. Jukes , R Holmquist , H Moise
关键词:
摘要: Distribution of amino acids in 68 representative proteins is compared with their distribution among 61 codons the genetic code. Average amounts lysine, aspartic acid, glutamic and alanine are above levels anticipated from code, arginine, serine, leucine, cysteine, proline, histidine below such levels. Arginine plus lysine account for 11.0 percent acid 11.3 percent; thus average charge roughly neutral.
sciencemag.org
harvard.edu参考文章(5)
Richard Holmquist, Deviations from compositional randomness in eukaryotic and prokaryotic proteins: the hypothesis of selective-stochastic stability and a principle of charge conservation. Journal of Molecular Evolution. ,vol. 4, pp. 277- 306 ,(1975) , 10.1007/BF01732532
Jack L. King, Non-Darwinian Evolution Science. ,vol. 164, pp. 788- 798 ,(1969) , 10.1126/SCIENCE.164.3881.788
R. E. FEENEY, R. HOFMANN, Depression of Freezing Point by Glycoproteins from an Antarctic Fish Nature. ,vol. 243, pp. 357- 359 ,(1973) , 10.1038/243357A0
Gerald R. Reeck, Lloyd Fisher, A STATISTICAL ANALYSIS OF THE AMINO ACID COMPOSITIONS OF PROTEINS International Journal of Peptide and Protein Research. ,vol. 5, pp. 109- 117 ,(2009) , 10.1111/J.1399-3011.1973.TB02325.X
Thomas H. Jukes, Arginine as an evolutionary intruder into protein synthesis Biochemical and Biophysical Research Communications. ,vol. 53, pp. 709- 714 ,(1973) , 10.1016/0006-291X(73)90151-4