作者: Bettina A Moser , Paul Russell
DOI: 10.1016/S1369-5274(00)00152-1
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摘要: Cdc2, a cyclin-dependent kinase, controls cell cycle progression in fission yeast. New details of Cdc2 regulation and function have been uncovered recent studies. These studies involve cyclins that associate with G1-phase the proteins regulate inhibitory phosphorylation during S-phase G2-phase. Recent investigations also provided better understanding DNA replication are directly or indirectly controlled by Cdc2.