Ether-linked heteroaryl compounds

作者: Pei-Pei Kung

DOI:

关键词:

摘要: Compounds of formula (I) are disclosed, as well methods for synthesizing such compounds and their use. Preferred potent inhibitors c-MET/HGFR useful in the treatment a variety HGFR-mediated disorders, including cancers.

参考文章(8)
Fusayo c, Sachi c, Itaru c, Junji c, Atsumi c, Takako c, Yasuyuki c, Yuji c, Tomohiro c, Tatsuo c, Kenji c, Yasuhiro c, Yoshio c, Keiko c, Kazuki c, Junichi c, Akihiko c, Ken-ichi c, Katsuji c, Hiroshi c, Masayuki c, Toru c, Nitrogenous aromatic ring compounds as anti cancer agents ,(2001)
Michele Potashman, Daniel Elbaum, Jr. Benny C. Askew, Gregory J. Habgood, Der Plas Simon Van, Julie Germain, Jean-Christophe Harmange, Joseph L. Kim, Lucian V. Dipietro, Vinod F. Patel, Fused azoles such as 2,5-disubstituted benzimidazoles, benzoxazoles and benzothiazoles as kinase inhibitors ,(2004)
M. Paul Chiarelli, Hua-Ping Wu, Alexandra M. Antunes, Paula S. Branco, Product ion studies of some novel arylamine adducts of deoxyguanosine by matrix-assisted laser desorption/ionization and post-source decay. Rapid Communications in Mass Spectrometry. ,vol. 13, pp. 2004- 2010 ,(1999) , 10.1002/(SICI)1097-0231(19991030)13:20<2004::AID-RCM745>3.0.CO;2-M
Yoshiko Iyaku Tansaku Kenkyusho Kobayashi, Hideko Iyaku Tansaku Kenkyusho Murooka, Toshiyuki Iyaku Tansaku Kenkyusho Shimizu, Shinichi Iyaku Tansaku Kenkyusho Ohyama, Shinichiro Iyaku Tansaku Kenkyusho Kato, Tsuyoshi Iyaku Tansaku Kenkyusho Nishitoba, Kazuo Iyaku Tansaku Kenkyusho Kubo, Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same ,(1996)
Terufumi Senga, Kazuhide Nakamura, Yasunari Fujiwara, Tatsushi Osawa, Atsushi Miwa, Tsuyoshi Nishitoba, Quinoline derivative and quinazoline derivative inhibiting self-phosphorylation of hepatocytus proliferator receptor, and medicinal composition containing the same ,(2002)
Samir Bennabi, Heike Heckroth, Joachim Mittendorf, Marcus Bauser, Heimo Ehmke, Klaus Münter, Dieter Lang, Santiago Figueroa Perez, Raimund Kast, Achim Feurer, Hartmut Schirok, Mark Jean Gnoth, Johannes-Peter Stasch, Pyrrolopyridine-substituted benzol derivatives for treating cardiovascular diseases ,(2004)
Christopher L. Autry, Matthew A. Marx, Michael J. Luzzio, Thienopyridine and thienopyrimidine anticancer agents ,(2002)
Joachim Mittendorf, Heimo Ehmke, Klaus Münter, Dieter Lang, Santiago Figueroa Perez, Achim Feurer, Hartmut Schirok, Jean Mark Gnoth, Raimund Kast, Samir Bennabi, Johannes-Peter Stasch, Heike Heckroth, Heteroaryloxy-substituted phenylaminopyrimidines as rho-kinase inhibitors ,(2003)