作者: Nan Li , Li Qi , Ying Shen , Juan Qiao , Yi Chen
DOI: 10.1021/AM505427J
关键词:
摘要: In this study, oligo(ethylene glycol) (OEG)-based thermoresponsive molecularly imprinted polymers (MIPs) for lysozyme on the surface of magnetic nanoparticles were synthesized. Thermoresponsive monomer 2-(2-methoxyethoxy)ethyl methacrylate, chelate N-(4-vinyl)-benzyl iminodiacetic acid, and acidic methacrylic acid selected as ingredients preparing MIP layer. The behavior novel was evaluated by dynamic light scattering swelling ratios measurements. Interestingly, in analysis lysozyme, capture/release process could be modulated changing temperature, avoiding tedious washing steps. Meanwhile, high adsorption capacity (204.1 mg/g) good selectivity capturing achieved. Additionally, imprinting with substrate allowed short time (2 h) rapid separation. Furthermore, proposed used to s...