Multi-chamber electroosmosis using textile reinforced agar membranes – A promising concept for the future of hemodialysis

作者: Markus Kofler , Margit Lenninger , Gert Mayer , Hannes Neuwirt , Michael Grimm

DOI: 10.1016/J.CARBPOL.2015.09.013

关键词:

摘要: Renal replacement therapy options are limited to hemodialysis and peritoneal dialysis (70% of US patients) or renal transplantation. Diffusion processes the main physico-chemical principle behind hemodialysis. An alternative way achieve liquid flow through membranes bases on electroosmotic which is observed as electrokinetic phenomenon in porous bear surface charges. Agar consists non-ionic agarose negatively charged agaropectine thus an flux analytical electrophoresis. In this study potential electroosmosis textile reinforced agar separation method was investigated. Using a five-chamber electrolysis cell membrane/cellulose fabric composite intensive 1-2 ml cm(2) h(-1) at 100 mA current could be observed. The movement cations structure led flux, also transported uncharged molecules such urea, glucose membrane. Separation low molecular weight determined by membrane characteristic. transport ions (K(+), PO4(3-), creatinine) (urea, glucose) experiments monitored using pH 5.5 phosphate electrolyte with aim assess overall electrochemical cell. results demonstrate for filtration biological fluids absence external pressure high shear rates.

参考文章(16)
Ana T Lima, Pieter J Kleingeld, Katja Heister, JP Gustav Loch, None, In situ electro-osmotic cleanup of tar contaminated soil—Removal of polycyclic aromatic hydrocarbons Electrochimica Acta. ,vol. 86, pp. 142- 147 ,(2012) , 10.1016/J.ELECTACTA.2011.12.060
Artur Cavaco-Paulo, Jose Morgado, Luis Almeida, Douglas Kilburn, Indigo Backstaining During Cellulase Washing Textile Research Journal. ,vol. 68, pp. 398- 401 ,(1998) , 10.1177/004051759806800602
William H. Fissell, Shuvo Roy, Andrew Davenport, Achieving more frequent and longer dialysis for the majority: wearable dialysis and implantable artificial kidney devices. Kidney International. ,vol. 84, pp. 256- 264 ,(2013) , 10.1038/KI.2012.466
George F. Vande Woude, Frank F. Davis, Barrier electrophoresis: A new electrophoretic technique Analytical Biochemistry. ,vol. 6, pp. 240- 250 ,(1963) , 10.1016/0003-2697(63)90131-3
Christoph Eisner, Robert Faulhaber-Walter, Yaohui Wang, Asada Leelahavanichkul, Peter S.T. Yuen, Diane Mizel, Robert A. Star, Josephine P. Briggs, Mark Levine, Jurgen Schnermann, Major contribution of tubular secretion to creatinine clearance in mice. Kidney International. ,vol. 77, pp. 519- 526 ,(2010) , 10.1038/KI.2009.501
Claudio Cameselle, Krishna R. Reddy, Development and enhancement of electro-osmotic flow for the removal of contaminants from soils Electrochimica Acta. ,vol. 86, pp. 10- 22 ,(2012) , 10.1016/J.ELECTACTA.2012.06.121
V. V. Polevoi, Electroosmotic Phenomena in Plant Tissues Biology Bulletin. ,vol. 30, pp. 133- 139 ,(2003) , 10.1023/A:1023285121361
S McLaughlin, R T Mathias, Electro-osmosis and the reabsorption of fluid in renal proximal tubules. The Journal of General Physiology. ,vol. 85, pp. 699- 728 ,(1985) , 10.1085/JGP.85.5.699