Total and ionized magnesium testing in the surgical intensive care unit - Opportunities for improved laboratory and pharmacy utilization

摘要: Abstract Purpose Ionized fraction (iMg) is the physiologically active form of magnesium (Mg); total Mg may not accurately reflect iMg status. Erroneously “low” levels result in unnecessary repetitive testing. Materials and methods From 11/2015 to 01/2016, patients ordered for from a pilot ICU also had tested. Weighted kappa statistic was used assess agreement between categories (low, normal, high). Predictors repeated testing repletion using data were explored through logistic regression models GEE techniques account measurements both bivariate multivariable analyses. Results There 470 Mg/iMg paired 173 patients. The weighted 0.35 (95%CI 0.27–0.43) indicating poor assessment Of 34 Mg samples reported as “low”, only 6 (18%) considered concurrent In models, history atrial fibrillation (aOR = 1.61, 95%CI 1.16–2.21, p = 0.004) concomitant metoclopramide (aOR = 1.71, 1.03–2.81, p = 0.036) significant predictors repeat Conclusions surgical ICU, categorical high) iMg. Over 80% values are erroneous additional repletion.