Studies of deoxyribonucleic acid synthesis and cell growth in the deoxyriboside requiring bacteria, Lactobacillus acidophilus

摘要: 1. 1. Depletion of the deoxyriboside requirement Lactobacillus acidophilus R-26 inhibits almost completely DNA synthesis and cell division, but little affects or RNA protein. 2. 2. Omission uracil from medium causes a parallel inhibition protein formation; is stimulated in absence uracil. 3. 3. Addition excess thymidine to cells previously starved both remarkable accumulation acid-soluble deoxyribosidic compounds active DNA, with no concurrent increase protein, number. Simultaneous addition chloramphenicol abolishes small observed under such conditions, effect on synthesis. 4. 4. Despite fact that synthesized actively increase, omission amino acids uracil-deficient as well complete strongly DNA.