Treatment with high-dose recombinant human hyaluronidase-facilitated subcutaneous immune globulins in patients with juvenile dermatomyositis who are intolerant to intravenous immune globulins: a report of 5 cases

作者: Fabian Speth , Johannes-Peter Haas , Claas H. Hinze

DOI: 10.1186/S12969-016-0112-6

关键词:

摘要: Background High-dose intravenous immune globulins (IVIg) are frequently used in refractory juvenile dermatomyositis (JDM) but often poorly tolerated. High-dose recombinant human hyaluronidase-facilitated subcutaneous (fSCIg) allow the administration of much higher doses than conventional globulin therapy and may be an alternative to IVIg. The safety efficacy fSCIg JDM is unknown.

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