Cancer in neck nodes with unknown primary site: role of mucosal radiotherapy.

作者: Christopher S. Harper , William M. Mendenhall , James T. Parsons , Scott P. Stringer , Nicholas J. Cassisi

DOI: 10.1002/HED.2880120603

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摘要: Sixty-nine patients with metastatic squamous cell carcinoma in neck nodes an unknown primary lesion were treated curative intent between October 1964 and December 1986. Sixty-five received radiotherapy to the at least part of mucosa head neck, whereas 4 treatment only. Mucosal doses approximately 5,000 cGy-6,000 cGy 170 cGy-180 per fraction. Eight (12%) subsequently developed mucosal site failures, a figure that did not differ significantly from incidence second metachronous cancer following definitive irradiation series 393 lesions supraglottic larynx, pharyngeal wall, pyriform sinus, or tonsillar area. This suggests was highly effective preventing appearance which metastasis arose. Absolute cause-specific 5-year survival rates 48% 66%, respectively.

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