作者: Samir N. Khleif , Helen Frederickson
DOI: 10.1007/978-1-4615-1657-6_12
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摘要: From 1796, when Edward Jenner infected a young boy with cowpox in hopes of preventing smallpox, to the present day, vaccinations have changed incidence many diseases worldwide. The history immunology actually predates ancient China, India and Persia. observation that recovery from particular disease rendered people “immune” second episode same disease, led Chinese try prevent smallpox by exposing uninfected pustule samples obtained lesions. then improved safety vaccination using different, but similar, virus vaccinate rather than him authentic virus. His observations milkmaids who had developed lesions did not develop “vaccinate” twenty-three other publish his findings 1801 (1). This initial experiment serves as an important foundation modern day immunology, served popularize term “vaccine”, which is derived Latin word “vacca”, means cow. Years later, Louis Pasteur, advanced germ theory infection, was able prove could be prevented exposure “weakened” germs, only caused harmless infections. theories supported development rabies vaccine.