Asymmetric synthesis of (+)-preussin from N-sulfinyl δ-amino β-ketoesters
作者： Franklin A Davis , Jianghe Deng
DOI: 10.1016/J.TET.2004.03.094
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摘要: Abstract The efficient asymmetric synthesis of the antifungal pyrrolidine alkaloid (+)-preussin ( 2 ) was accomplished via stereoselective reduction a 5-substituted 3-oxo proline. oxo proline prepared from an N-sulfinyl δ-amino β-ketoester, sulfinimine derived polyfunctionalized chiral building block.
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