Gut mucosa morphology and microflora changes in malnourished mice after renutrition with milk and administration of Lactobacillus casei.

摘要: Nutrition plays a key role in maintaining the balance of intestinal microflora. Malnutrition disturbs ecological barrier and induces histological damage. We evaluated modifications induced by renutrition with nonfat milk (NFM) Lactobacillus casei administration (for 2 days) on bacterial gut population structural ultrastructural malnourished mice. Balb/c mice suffering from malnutrition process immediately after weaning 21 were divided into four groups given NFM for 0, 7, 14, days. Another group was treated similar way, but different periods administration, this received L. two consecutive All experimental animals sacrificed cervical dislocation, both microflora structure intestine studied. In animals, decrease numbers anaerobic microorganisms observed, whereas there an increase number Enterobacteriaceae. plus casei, we could observe important improvement small large intestines no differences between treatments. Structural studies showed slight 7 days treatment NFM, 14 renutrition, normal villi, additional feeding days, yielded earlier (7 days).