Determination of irritant threshold concentrations of multiple tree, grass, weed and mould allergens for intradermal testing of horses residing in the southern USA

摘要: Background Appropriate allergen threshold concentrations (TCs) for intradermal testing (IDT) have not been established in horses many pollen and mould allergens. Objectives To determine the TCs non-allergic describe frequency of late phase reactions 26 allergens, including trees, grasses, weeds moulds residing southern Unites States. Animals Twenty four clinically normal United States. Methods Threshold different allergens were determined using IDT subjective measurements at 30 minutes. Delayed evaluated 4 24 h. Results Threshold (all PNU/mL) eight tree (black willow 1,000, box elder live oak pecan 2,000, white ash 4,000, red mulberry 2,000 green 2,000); two grass (Johnson 250 PNU/mL Kentucky blue 500 PNU/mL); (carelessweed 1,000 PNU/mL, great ragweed one (Curvularia 8,000 PNU/mL). The TC was due to excessive reactivity lowest concentration tested (1,000 bahia perennial rye grass. Eleven other did meet criteria establish a when min lack positive reactions. Multiple caused ≥10% h. Reactions h rare with exception horse. Conclusions clinical importance This study identified multiple horses. These values may prove useful optimizing allergic