Evaluation of effect of scopolamine on stages of active avoidance learning in rats

作者: M. Dikshit , A. Das , C. Nath , H. K. Singh

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摘要: Objective: To investigate the effect of scopolamine administered at different stages learning and memory process in active avoidance task rats. Methods: Adult male Sprague-Dawley rats were trained on task. Each animal received a daily session 15 trials for 5 days i.e., maximum 75 trials. Scopolamine (3 mg/kg, i.p) was time points according to acquisition, consolidation recall three groups (n=8). Increase response 5th as compared 1st taken criteria failure considered dementia. Results: There significant increase control group. Among treated groups, most marked dementia observed group that after last trial session. Conclusion: Results this study show preferentially affects acquisition process.

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