Management of early breast cancer in older women: from screening to treatment.

摘要: Background Breast cancer is a common condition. It leading cause of death among women, and its incidence increases with age. Aging the population improvement quality life elders make it major public health issue. We reviewed literature to try determine management breast in older women. Methods conducted narrative review by searches using key words "breast cancer", "elderly older", "women" Pubmed, Scopus, Google Scholar. The aim this summarize early women discussing controversies screening Then, we define optimal strategy for these either surgery alone or primary endocrine therapy. also discuss indications lymph node dissection, evaluate benefit adjuvant radiotherapy, chemotherapy, anti HER2 treatment Results More than 50% patients are 65 years older, around 30% more 70 old. Most randomized trials did not include Hence, based on provided younger Regardless age, must best efficiency. Advanced age itself should be limitation treatment. There no standard guidelines set elderly patients. Surgical evolved avoid mastectomy, conservative mammary was proposed, similar that used proportion receiving radiotherapy increasing. role analyzed. Adjuvant chemotherapy beneficial hormone receptor-negative tumors. In those receptor-positive tumors, association trastuzumab HER2-positive HER2-negative tumors hormonal therapy very good option. Conclusion This requires particular adapted management. essential included new clinical individualized recommendation.