Spinal cord lesions of myelitis with hyperIgEemia and mite antigen specific IgE (atopic myelitis) manifest eosinophilic inflammation.

作者: Hitoshi Kikuchi , Manabu Osoegawa , Hirofumi Ochi , Hiroyuki Murai , Izumi Horiuchi

DOI: 10.1016/S0022-510X(00)00475-5

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摘要: We report the neuropathological findings of spinal cord specimens obtained from two patients who had localized myelitis with hyperIgEemia and mite antigen specific IgE (atopic myelitis). Both cases showed mild dysfunction, gadolinium-enhanced area isolated lesion observed on MRI was biopsied, respectively. Neuropathologically, both many perivascular lymphocyte cuffings associated disrupted vessels, infiltration eosinophils in lesions. myelin axons were lost lesions, which astrogliosis. These suggest that an allergic mechanism may play a role this condition.

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