Quantitative analysis of β-adrenergic blocking agents by NMR spectroscopy

作者: M.A. Iorio , A.Mazzeo Farina , A. Doldo

DOI: 10.1016/0731-7085(87)80002-X

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摘要: Abstract The quantitative analysis by 1 H NMR of labetalol, oxprenolol and four other β-adrenergic blocking agents is described. method depends on the integration selected resonances analyte an internal reference which do not overlap. Procedures for extraction from tablets are given corrections due to features excipients outlined in some cases. reasonably precise rapid, assay results compare favourably with those obtained a UV procedure.

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