Modeling insect olfactory neuron signaling by a network utilizing disinhibition

作者: Evyatar Av-Ron , Jean-Pierre Rospars

DOI: 10.1016/0303-2647(95)01531-O

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摘要: A male moth locates a conspecific female by detecting her sexual-pheromone blend. This detection is carried out in the antennal lobe, first stage of olfactory information processing, where local inhibitory neurons and projection (relay) interact. Antennal-lobe exhibit low-frequency ( 100 Hz) activity response to pheromone stimulation. We describe this behavior realistic biophysical neuron model. The bursting model result both intrinsic cellular properties network interaction. slowly activating inactivating calcium channel provides depolarizing current for disinhibition shown be feasible mechanism triggering channel. Small neural networks utilizing are presented with intercalated between receptor neurons. firing behaviors stimulation blend or its components accordance experimental results. architecture offers an alternative view processing from classical derived vertebrate studies.

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