Multiple indicators of ambient and personal ultraviolet radiation exposure and risk of non-Hodgkin lymphoma (United States)

作者: D. Michal Freedman , Michael G. Kimlin , Richard W. Hoffbeck , Bruce H. Alexander , Martha S. Linet

DOI: 10.1016/J.JPHOTOBIOL.2010.08.001

关键词:

摘要: Recent epidemiologic studies have suggested that ultraviolet radiation (UV) may protect against non-Hodgkin lymphoma (NHL), but few, if any, assessed multiple indicators of ambient and personal UV exposure. Using the US Radiologic Technologists study, we examined association between NHL self-reported time outdoors in summer, as well average year-round seasonal exposures based on satellite estimates for different age periods, sun susceptibility participants who had responded to two questionnaires (1994–1998, 2003–2005) were cancer-free earlier questionnaire. unconditional logistic regression, estimated odds ratio (OR) 95% confidence intervals 64,103 with 137 cases. Self-reported summer was unrelated risk. Lower risk somewhat related higher winter exposure period closest time, prior to, diagnosis (ages 20–39). Relative 1.0 lowest quartile UV, OR successively quartiles 0.68 (0.42–1.10); 0.82 (0.52–1.29); 0.64 (0.40–1.03), p-trend = 0.06), this period. The lower associated provides modest additional support a protective relationship NHL.

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