Variation in hormone receptor and HER-2 status between primary and metastatic breast cancer: review of the literature.
作者： Cagatay Arslan , Ebru Sari , Sercan Aksoy , Kadri Altundag
DOI: 10.1517/14656566.2011.537260
关键词:
摘要: Importance of the field: Hormone and human epidermal growth factor receptor 2 (HER-2) receptors are two important pharmaceutical targets that affect survival patients with metastatic breast cancer. Discordance hormone HER-2 were reported in a series studies. Receptor status was to change both directions, yet alteration occurs mostly loss positivity for receptors. We do not know exact mechanism this process or contribution rate technical mistakes; number mechanisms might be responsible. Factors suggested include: tumor heterogeneity, clonal selection cell subpopulations, genetic instability cells, local systemic treatments, time interval between primary metastasis, determination techniques, site metastasis. Areas covered review: Studies estrogen, progesterone discordance metastasis cancer summarized. Labor...
informahealthcare.com参考文章(55)
C. Kent Osborne, William L. McGuire, Gary M. Clark, William A. Knight, Gary C. Chamness, Donald F. Hull, Multiple estrogen receptor assays in human breast cancer. Cancer Research. ,vol. 43, pp. 413- 416 ,(1983)
Georgia Bardi, Georgia Bardi, Nikos Pandis, Nikos Pandis, Manuel R. Teixeira, Johan A. Andersen, Severre Heim, Karyotypic comparisons of multiple tumorous and macroscopically normal surrounding tissue samples from patients with breast cancer Cancer Research. ,vol. 56, pp. 855- 859 ,(1996)
R.S. Kerbel, Growth dominance of the metastatic cancer cell: cellular and molecular aspects. Advances in Cancer Research. ,vol. 55, pp. 87- 132 ,(1990) , 10.1016/S0065-230X(08)60469-8
T Kuukasjärvi, J Kononen, H Helin, K Holli, J Isola, Loss of estrogen receptor in recurrent breast cancer is associated with poor response to endocrine therapy. Journal of Clinical Oncology. ,vol. 14, pp. 2584- 2589 ,(1996) , 10.1200/JCO.1996.14.9.2584
Yoshihisa Umekita, Yoshiatsu Sagara, Hiroki Yoshida, Estrogen receptor mutations and changes in estrogen receptor and progesterone receptor protein expression in metastatic or recurrent breast cancer. Japanese Journal of Cancer Research. ,vol. 89, pp. 27- 32 ,(1998) , 10.1111/J.1349-7006.1998.TB00475.X
C Kamby, B Bruun Rasmussen, B Kristensen, Oestrogen receptor status of primary breast carcinomas and their metastases. Relation to pattern of spread and survival after recurrence. British Journal of Cancer. ,vol. 60, pp. 252- 257 ,(1989) , 10.1038/BJC.1989.264
Maciej Kmieciak, Keith L. Knutson, Catherine I. Dumur, Masoud H. Manjili, HER-2/neu antigen loss and relapse of mammary carcinoma are actively induced by T cell-mediated anti-tumor immune responses. European Journal of Immunology. ,vol. 37, pp. 675- 685 ,(2007) , 10.1002/EJI.200636639
Ebru Sari, Gulnur Guler, Mutlu Hayran, Ibrahim Gullu, Kadri Altundag, Yavuz Ozisik, Comparative study of the immunohistochemical detection of hormone receptor status and HER-2 expression in primary and paired recurrent/metastatic lesions of patients with breast cancer Medical Oncology. ,vol. 28, pp. 57- 63 ,(2011) , 10.1007/S12032-010-9418-2
Elyse E. Lower, Eleanor L. Glass, Deborah A. Bradley, Robbin Blau, Sue Heffelfinger, Impact of Metastatic Estrogen Receptor and Progesterone Receptor Status on Survival Breast Cancer Research and Treatment. ,vol. 90, pp. 65- 70 ,(2005) , 10.1007/S10549-004-2756-Z
Richard Anthony Hawkins, Robert Black, Robert James Campbell Steele, John Michael Joseph Dixon, Andrew Patrick McEwan Forrest, None, Oestrogen receptor concentration in primary breast cancer and axillary node metastases Breast Cancer Research and Treatment. ,vol. 1, pp. 245- 251 ,(1981) , 10.1007/BF01806264