4-dimensional computed tomography imaging and treatment planning.

摘要: In the era of conformal therapy and intensity-modulated therapy, there is an increased desire to raise tumor dose facilitate improved survival decrease normal tissue reduce treatment-related complications. Setup accuracy internal motion limit our ability margins. Internal has both interfraction intrafraction components, although only component will be addressed here. Intrafraction significant for lung, liver, pancreatic radiotherapy a lesser extent breast prostate radiotherapy. A method explicitly account temporally adjust treatment beam based on position with time such that radiation synchronized motion. This addition into 3-dimensional process termed 4-dimensional (4D) Four-dimensional may allow safe clinical target volume-planning volume margin reduction achieve goals raised decreased dose. article discusses methodology 4D CT imaging planning, some comments delivery.