Molecular farming – The slope of enlightenment

作者: Rainer Fischer , Johannes F. Buyel

DOI: 10.1016/J.BIOTECHADV.2020.107519

关键词:

摘要: … Plants did not have a track record of success in pharmaceutical protein manufacturing, lacked … is now climbing the slope of enlightenment and will soon emerge as a mature technology. …

参考文章(107)
Rita B. Santos, Rita Abranches, Rainer Fischer, Markus Sack, Tanja Holland, Putting the Spotlight Back on Plant Suspension Cultures Frontiers in Plant Science. ,vol. 7, pp. 297- 297 ,(2016) , 10.3389/FPLS.2016.00297
E. Vamvaka, A. Evans, K. Ramessar, L. R. H. Krumpe, R. J. Shattock, B. R. O’Keefe, P. Christou, T. Capell, Cyanovirin-N produced in rice endosperm offers effective pre-exposure prophylaxis against HIV-1BaL infection in vitro. Plant Cell Reports. ,vol. 35, pp. 1309- 1319 ,(2016) , 10.1007/S00299-016-1963-5
Anna Hofbauer, Eva Stoger, Subcellular accumulation and modification of pharmaceutical proteins in different plant tissues. Current Pharmaceutical Design. ,vol. 19, pp. 5495- 5502 ,(2013) , 10.2174/1381612811319310005
Matilde Merlin, Mario Pezzotti, Linda Avesani, Edible plants for oral delivery of biopharmaceuticals British Journal of Clinical Pharmacology. ,vol. 83, pp. 71- 81 ,(2017) , 10.1111/BCP.12949
Somen Nandi, Aaron T. Kwong, Barry R. Holtz, Robert L. Erwin, Sylvain Marcel, Karen A. McDonald, Techno-economic analysis of a transient plant-based platform for monoclonal antibody production. mAbs. ,vol. 8, pp. 1456- 1466 ,(2016) , 10.1080/19420862.2016.1227901
, A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection. The New England Journal of Medicine. ,vol. 375, pp. 1448- 1456 ,(2016) , 10.1056/NEJMOA1604330
Stefan Schillberg, Nicole Raven, Rainer Fischer, Richard M. Twyman, Andreas Schiermeyer, Contained Molecular Farming Using Plant Cell and Tissue Cultures John Wiley & Sons, Ltd. pp. 259- 281 ,(2017) , 10.1002/9783527800599.CH9
Uri Hanania, Tami Ariel, Yoram Tekoah, Liat Fux, Maor Sheva, Yehuda Gubbay, Mara Weiss, Dina Oz, Yaniv Azulay, Albina Turbovski, Yehava Forster, Yoseph Shaaltiel, Establishment of a tobacco BY2 cell line devoid of plant-specific xylose and fucose as a platform for the production of biotherapeutic proteins. Plant Biotechnology Journal. ,vol. 15, pp. 1120- 1129 ,(2017) , 10.1111/PBI.12702
Sébastien Mercx, Nicolas Smargiasso, François Chaumont, Edwin De Pauw, Marc Boutry, Catherine Navarre, None, Inactivation of the β(1,2)-xylosyltransferase and the α(1,3)-fucosyltransferase genes in Nicotiana tabacum BY-2 cells by a multiplex CRISPR/Cas9 strategy results in glycoproteins without plant-specific glycans Frontiers in Plant Science. ,vol. 8, pp. 403- 403 ,(2017) , 10.3389/FPLS.2017.00403
J.F. Buyel, R.M. Twyman, R. Fischer, Very-large-scale production of antibodies in plants: The biologization of manufacturing. Biotechnology Advances. ,vol. 35, pp. 458- 465 ,(2017) , 10.1016/J.BIOTECHADV.2017.03.011