Sensitivity of human and murine hemopoietic precursor cells to chemotherapeutic agents assessed in cell culture.

作者: Makio Ogawa , Daniel E. Bergsagel , E. A. McCulloch

DOI: 10.1182/BLOOD.V42.6.851.851

关键词:

摘要: The sensitivity of human and murine hemopoietic precursor cells to 1,3 bis (2 chloroethyl)-1-nitrosourea (BCNU), nitrogen mustard, 5-fluorouracil, melphalan was assessed in culture using colony assay techniques. results indicate that may differ their intrinsic drugs. hematologic toxicity some chemotherapeutic agents cannot be extrapolated directly from mouse man.

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