A combined experimental and numerical approach to explore tribocharging of pharmaceutical excipients in a hopper chute assembly

摘要: Abstract Electrostatic charging via contact electrification or tribocharging refers to the process of charge transfer between two solid surfaces when they are brought into with each other and separated. Charging continuous particulate flows on is poorly understood has often been empirical. This study aims toward understanding pharmaceutical excipients using a simplified geometry unidirectional flow in hopper–chute assembly. Assuming electron be dominant mechanism electrification, triboelectric series was generated work functions estimated from quantum chemical calculations. A 3D-DEM model developed employing electrostatic forces. Using numerical simulations, accumulation for an assemblage particles during determined under different conditions. To theoretically analyze charging, parametric studies affecting powder have investigated. higher specific observed at larger friction coefficients lower restitution coefficients. The results obtained simulation reinforce collisional nature triboelectrification. revealed similar trends experimental observations. However, enable priori prediction needs tested additional materials extended operations.