Elevated T cell activation score is associated with improved survival of breast cancer.
作者： Lingeng Lu , Yalai Bai , Zuoheng Wang
DOI: 10.1007/S10549-017-4281-X
关键词:
摘要: Purpose Immune checkpoints cytotoxic T lymphocyte antigen 4 (CTLA4) and programmed cell death 1 receptor (PD-1) negatively regulate CD8+ functions, impeding the capacity of effector cells to kill tumors. Here, we study prognostic significance CTLA4, PD-1 activation status in breast cancer.
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