作者: Jennifer S. Walsh , Margaret A. Paggiosi , Richard Eastell
DOI: 10.1210/JC.2012-1677
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摘要: Context: Bone size, geometry, density, and microarchitecture are important determinants of bone strength. By understanding how these properties change during skeletal development, we can better understand fragility. Objectives: The aim the study was to compare microarchitecture, strength radius tibia in men women at end adolescence young adulthood relate biochemical turnover markers regulatory hormones. Design: We conducted a cross-sectional 116 healthy ages 16–18 (n = 56) 30–32 60) yr. Outcome Measures: used high-resolution peripheral quantitative computed tomography measure distal micro-finite element modeling estimate measured (β C-terminal telopeptide type I collagen amino-terminal propeptide procollagen) hormones known affect me...