Taking Risks in Complex Synthesis Design
作者： Erik J. Sorensen , David A. Siler , Jeffrey D. Mighion
DOI: 10.1016/B978-0-08-099362-1.00009-6
关键词:
摘要: Abstract This chapter defines risk-taking in organic synthesis as the deliberate pursuit of strategies that do not have near neighbors chemical literature. In these ventures into unknown, behavior can be difficult to predict. The literature chemistry is replete with examples powerful, bond-forming had little or no precedent when they were developed. essay addresses some those an effort demonstrate merits creative planning and execution syntheses.
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