Lithocholic acid derivative in the presence of dimethyl sulfoxide: Morphology and phase transitions

摘要: Abstract We report on the properties of a new organogelator, which is an ether derivative lithocholic acid (7OPhOLCA). The correctness chemical structure and purity 7OPhOLCA was confirmed by thin layer chromatography, proton nuclear magnetic resonance (1H NMR) spectroscopy, elemental analysis (EA) infrared spectroscopy (IR). Phase transition temperatures enthalpies gel were obtained differential scanning calorimetry (DSC) polarizing optical microscopy (POM). Changes in vibrational spectra depending temperature modifications studied using technique FTIR Spectroscopy with 2D correlation analysis. small angle neutron scattering method (SANS) used to determine morphology internal investigated system. It found that substance forms non-transparent stable spherulite organization at macro-scale level. self-assemblies nano-scale level are quite different variation Gel phase. A further increase leads formation sol phase again. turns out gel-sol changes significantly concentration 7OPhOLCA. results DSC SANS measurements indicated reversible behavior Gel-SolGel hysteresis during heating cooling.