Prognostic value of peripheral blood lymphocyte-to-monocyte ratio in patients with solid tumors: a meta-analysis
作者： Bao-sheng Li , Junjie Teng , Jian Zhang , Tianyi Zhang , Shu Zhang
DOI: 10.2147/OTT.S94458
关键词:
摘要: Background Although accumulating evidence suggests peripheral blood lymphocyte-to-monocyte ratio (LMR) could act as a prognosis predictor in various tumors, the prognostic value of LMR still remains controversial. We carried out this meta-analysis to evaluate association pretreatment with survival outcomes patients solid tumors. Methods Eligible studies were collected and extracted by searching PubMed Embase databases up June 3, 2015. The pooled hazard ratios (HRs) their 95% confidence intervals (CIs) computed assess quantitatively. Results Eighteen total 8,377 participants enrolled meta-analysis. Our findings indicated that elevated pre-treatment predicted significantly favorable overall (HR=0.59, CI: 0.53-0.67) disease-free (HR=0.74, 0.68-0.80) tumor patients. Subgroup analyses revealed enhanced was associated digestive system cancers (HR=0.63, 0.49-0.81), urinary tract tumors (HR=0.66, 0.52-0.84), lung cancer (HR=0.62, 0.54-0.72), nasopharyngeal carcinoma (HR=0.50, 0.43-0.57). Conclusion This showed may indicate
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