Estudo das células Neuro2A sobre os biomateriais PCL e PLLA
作者： Luiz Gabriel Maturana , Amauri Pierucci , Gustavo Ferreira Simões , Alexandre Leite Rodrigues de Oliveira , Eliana Aparecida de Rezende Duek
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摘要: Resumo: Os biomateriais poli L-acido latico (PLLA) e o caprolactona (PCL) sao os polimeros mais estudadas na area dos materiais bioreabsorviveis. Dentre as suas principais caracteristicas que contribuem para a interacao celular, temos especificidade quimica da superficie, eletrica, hidrofobicidade topografia. Ainda, observa-se tempo de degradacao, porosidade, biocompatibilidade com tecido biologico, bem como, confeccao variadas formas dimensoes. Ja pratica cultura tem como objetivo estudar adesao, migracao, diferenciacao proliferacao celular utilizando-se um determinado material ou substância. Contudo, poucos trabalhos utilizando ora supracitados aplicacao em celulas neuro2A foram realizados. Sabe-se este tipo derivado embrionarias crista neural, quais originam neuronios simpaticos apresentam caracteristica imortalidade, portanto, excelentes modelos ensaios in vitro. Nesse sentido, presente estudo avalia adesao desta linhagem sobre biopolimeros (PLLA). Palavras-chave: Biomateriais, PLLA, PLC, neuroblastoma, cultura. Study of Neuro2a Cells on the Biomaterials Poly L-lactic Acid and Caprolactone
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