Vitamin D supplementation and bone mass accrual in underprivileged adolescent Indian girls.
作者： V. V. Khadilkar , M. G. Sayyad , Sadanand Naik , D. R. Bhandari , A. V. Khadilkar
DOI: 10.6133/APJCN.2010.19.4.03
关键词:
摘要: Vitamin D deficiency is common among children and adolescents in India, spite of abundant sunshine. We conducted a pilot; double blind randomised controlled trial to investigate the effect vitamin supplementation on bone mineral content underprivileged adolescent girls, Pune, India. Fifty post-menarcheal girls aged 14 15 years were receive 300,000 IU (7.5 mg) ergocalciferol or placebo orally, 4 times/year. All participants received 250 mg elemental calcium (calcium carbonate) daily. Outcome measures included change serum 25-hydroxyvitamin D, size adjusted area at total body lumbar spine. Post supplementation, median concentration was 75.2 (64.2-85.5) nmol/L intervention group 28.1 (16.7-34.0) group. Increment outcome not different two groups. However, there positive (p＜0.05), (p＜0.05) spine trend (p=0.07) who within 2 menarche. conclude that did have beneficial skeletal mineralization more than post menarcheal. significant area, ≤
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nhri.org.tw 参考文章(26)
R Mittal, S Rai, S K Upadhyay, K N Agarwal, D K Agarwal, R Prakash, Physical and sexual growth pattern of affluent Indian children from 5 to 18 years of age. Indian Pediatrics. ,vol. 29, pp. 1203- 1282 ,(1992)
Marie V. Krause, Food, nutrition and diet therapy ,(1972)
Raman K Marwaha, Nikhil Tandon, Devi Reddy HK Reddy, Rashmi Aggarwal, Rajvir Singh, Ramesh C Sawhney, Bobbin Saluja, M Ashraf Ganie, Satveer Singh, Vitamin D and bone mineral density status of healthy schoolchildren in northern India The American Journal of Clinical Nutrition. ,vol. 82, pp. 477- 482 ,(2005) , 10.1093/AJCN.82.2.477
B. V. Rama Sastri, C. Gopalan, S. C. Balasubramanian, Nutritive value of Indian foods National Institute of Nutrition, Indian Council of Medical Research. ,(1971)
G. M. Berlyne, J. Ben Ari, E. Nord, R. Shainkin, Bedouin osteomalacia due to calcium deprivation caused by high phytic acid content of unleavened bread The American Journal of Clinical Nutrition. ,vol. 26, pp. 910- 911 ,(1973) , 10.1093/AJCN/26.9.910
Gary M. Kiebzak, Larry J. Leamy, Lee M. Pierson, Russell H. Nord, Zhi Y. Zhang, Measurement precision of body composition variables using the lunar DPX-L densitometer. Journal of Clinical Densitometry. ,vol. 3, pp. 35- 41 ,(2000) , 10.1385/JCD:3:1:035
Robert P. Heaney, M. Susan Dowell, Cecilia A. Hale, Adrianne Bendich, Calcium Absorption Varies within the Reference Range for Serum 25-Hydroxyvitamin D Journal of The American College of Nutrition. ,vol. 22, pp. 142- 146 ,(2003) , 10.1080/07315724.2003.10719287
Heli T Viljakainen, Anna-Mari Natri, Merja Kärkkäinen, Minna M Huttunen, Anette Palssa, Jette Jakobsen, Kevin D Cashman, Christian Mølgaard, Christel Lamberg-Allardt, A Positive Dose–Response Effect of Vitamin D Supplementation on Site-Specific Bone Mineral Augmentation in Adolescent Girls: A Double-Blinded Randomized Placebo-Controlled 1-Year Intervention Journal of Bone and Mineral Research. ,vol. 21, pp. 836- 844 ,(2006) , 10.1359/JBMR.060302
Dennis R. Carter, Mary L. Bouxsein, Robert Marcus, New approaches for interpreting projected bone densitometry data Journal of Bone and Mineral Research. ,vol. 7, pp. 137- 145 ,(2009) , 10.1002/JBMR.5650070204
M. R. Clements, L. Johnson, D. R. Fraser, A new mechanism for induced vitamin D deficiency in calcium deprivation. Nature. ,vol. 325, pp. 62- 65 ,(1987) , 10.1038/325062A0