Cognitive-behavioural therapy and family intervention for relapse prevention and symptom reduction in psychosis: randomised controlled trial {

摘要: Background Family intervention reduces relapse rates in psychosis. Cognitive-behavioural therapy (CBT) improves positive symptoms but effects on are not established. Aims To test the effectiveness of CBT and family reducing relapse, improving functioning patients who had recently relapsed with non-affective Method A multicentre randomised controlled trial (ISRCTN83557988) two pathways: those without carers were allocated to treatment as usual or plus usual, usual. The focused prevention for 20 sessions over 9 months. Results total 301 83 participated. Primary outcome data available 96% sample. no remission days hospital at 12 24 For secondary outcomes, showed a beneficial effect depression months there intervention. In people carers, significantly improved delusional distress social functioning. Therapy did change key psychological processes. Conclusions Generic psychosis is indicated routine recovering from recent should currently be reserved distressing medication-unresponsive symptoms. Any targeted this acute population requires development. lack may attributable low overall rate carers.