Environmental Factors and Parkinson's Disease
作者： Caroline M. Tanner
DOI: 10.1016/B978-1-4160-6641-5.00008-8
关键词:
摘要: Publisher Summary This chapter provides updates on the investigations of environmental determinants Parkinson's disease (PD). PD is a complex disorder, with genetic and factors contributing to underlying pathogenesis disease. Exposure factor 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) was one first single causes parkinsonism identified. Cigarette smoking, use smokeless tobacco, passive exposure cigarette smoke have been associated lower risk PD. reduced in habitual coffee or tea drinkers. Uric acid may serve as biomarker for Greater physical activity adult life has The discusses challenges studying PD, some putative protective nonsteroidal anti-inflammatory drug use, specific toxicants, shared risks neurodegenerative disorders.
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