Overview: end-stage renal disease in the developing world.

摘要: Abstract: Although the vast majority of patients with end-stage renal disease (ESRD) worldwide live in what is called developing world, little known about its epidemiology and management. With current paucity credible adequately representative registries, it justified to resort innovative means obtaining information. In this attempt, world-renowned leading nephrologists 10 countries collaborated filling a 103-item questionnaire addressing epidemiology, etiology, management ESRD their respective on basis integrating available data from different sources. Through joint effort, was possible identify number important trends. These include expected high prevalence ESRD, despite limited access replacement therapy, dependence wealth. Glomerulonephritis, rather than diabetes, remains as main cause significant geographical variations prevailing histopathological types. The implementation modalities therapy (RRT) inhibited by lack funding, although governments, insurance companies, donations usually constitute major sponsors. Hemodialysis preferred modality most exception Mexico where chronic ambulatory peritoneal dialysis (CAPD) takes lead. several other countries, only for those transplant waiting list. Dialysis associated frequency complications particularly HBV HCV infections. Data HIV are lacking. Aluminum intoxication problem countries. Treatment withdrawal common socioeconomic reasons. Transplantation offered an average 4 per million population (pmp). Recipient exclusion criteria minimal. Donor selection generally loose regarding tissue typing, remote viral infection, and, some blood-relation recipient live-donor transplants. Cadaver donors accepted many participating survey. outcomes RRT are, average, inferior internationally acknowledged standards largely due infective cardiovascular complications.