CD2 related immunoregulation in oral cancer
作者： Prabha Balaram , Girija Meenattoor , K.R. Nalinakumari , N.K. Hareendran , T.K. Padmanabhan
DOI: 10.1016/0964-1955(94)90049-3
关键词:
摘要: Sera from 93 patients with carcinoma of the buccal mucosa were analysed for its regulatory effect on CD2 antigen expression using anti monoclonal antibodies and sheep erythrocyte rosetting assay. The sera 55.5% showed an inhibitory (blocker sera) while 44.5% enhancing (enhancer expression. An interesting feature observed was dominance enhancer in early stages cancer, well differentiated squamous cell verrucous carcinoma. had no correlation to concentration circulating immune complexes (CIC), ferritin, serum immunoglobulins individual basis. Taken as a whole, CIC higher IgG IgM blocker sera. groups better prognosis clinical practice suggest presence factors good prognosis. status patient is examined second phase study.
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