Direct electron transfer process of pyrroloquinoline quinone–dependent and flavin adenine dinucleotide–dependent dehydrogenases: Fundamentals and applications

作者: Nobuhumi Nakamura , Kouta Takeda

DOI: 10.1016/J.COELEC.2021.100747

关键词:

摘要: Abstract Pyrroloquinoline quinone–dependent and flavin adenine dinucleotide–dependent enzymes catalyze the oxidation of various compounds. These are large molecules, embedding active sites in insulating portion molecule generally make direct bioelectrocatalysis difficult. Dehydrogenases with a built-in electron transfer domain capable (DET) to an electrode. Attempts have also been made realize DET by artificially producing fusion proteins which protein engineering is fully exploited connect domains. Furthermore, reports without electrode started appear. This review summarizes recent on fundamental findings applications using DET-enzyme electrodes.

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