Association of Major and Minor ECG Abnormalities With Coronary Heart Disease Events
作者： Douglas C. Bauer
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摘要: Results At baseline, 276 participants (13%) had minor and 506 (23%) major ECG abnormalities. During follow-up, 351 CHD events (96 deaths, 101 acute MIs, 154 hospitalizations for angina or coronary revascularizations). Both baseline abnormalities were associated with an increased risk of after adjustment traditional factors (17.2 per 1000 person-years among those no abnormalities; 29.3 person-years; hazard ratio [HR], 1.35; 95% CI, 1.02-1.81; 31.6 HR, 1.51; 1.20-1.90; abnormalities). When added to a model containing alone, 13.6% intermediate-risk both correctly reclassified (overall net reclassification improvement [NRI], 7.4%; 3.1%-19.0%; integrated discrimination improvement, 0.99%; 0.32%-2.15%). After 4 years, 208 new 416 persistent subsequent (HR, 2.01; 1.33-3.02; 1.66; 1.18-2.34; respectively). the Framingham Risk Score, NRI was not significant (5.7%; �0.4% 11.8%). Conclusions Major older adults events. Depending on model, adding improved prediction beyond factors.
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