Chest physiotherapy in infants with cystic fibrosis: to tip or not? A five-year study.

摘要: There is controversy about the need for postural drainage physiotherapy in asymptomatic infants with cystic fibrosis (CF). We aimed to compare effectiveness of standard chest (SPT) a modified regimen without head-down tilt (MPT) young CF. Twenty newly diagnosed CF (mean age, 2.1 months; range, 1–4) were randomized SPT or MPT. Parents kept detailed symptom and treatment diary following 12 months. Serial radiographs, taken at diagnosis, months, 2½ years, 5 years after assessed using Brasfield score. Pulmonary function tests compared between groups years. Of 20 infants, 16 (80%) completed review 14 (70%) Patients receiving had more days upper respiratory tract symptoms than those on MPT (70 ± 32.8 vs. 37 ± 24.9 days; P = 0.04) required longer courses antibiotics (23 ± 28.5 14 ± 11.2 P = 0.05). Chest x-ray scores similar diagnosis but worse (P = 0.03). Forced vital capacity forced expired volume 1 sec (FEV1) 5–6 was lower (P < 0.05). In conclusion, associated fewer complications Pediatr Pulmonol. 2003; 35:208–213. © 2003 Wiley-Liss, Inc.