A subpopulation of preganglionic parasympathetic neurons in the rat contain adenosine deaminase.

摘要: Abstract Immunohistochemical staining and retrograde fluorescent tracing techniques were used to demonstrate the presence of adenosine deaminase in preganglionic parasympathetic neurons. Both brainstem sacral spinal cord nuclei found contain a subpopulation neurons immunoreactive for deaminase. Immunostaining was restricted group cells which shown by with Fast Blue project exclusively sphenopalatine ganglion. This defined as lacrimo-nasopalatine nucleus. Neurons all other cranial centers devoid immunoreactivity. In deaminase-immunoreactive intermediolateral gray matter region Injections into pelvic ganglion labeled large numbers this nucleus, only some contained The majority also be choline acetyltransferase both nuclei. present results show that subclass are among few structures central nervous system express what appear high levels observation together evidence suggesting purines serve neurotransmitters neuons supports notion may constitute marker adenine nucleoside and/or nucleotide neurotransmission.