Paracoccidioidomycosis in Immunocompromised Patients: A Literature Review.

摘要: Paracoccidioidomycosis (PCM) is an endemic mycosis found in Latin America that causes systemic disease mostly immunocompetent hosts. A small percentage of PCM occurs immunocompromised patients where low clinical suspicion the infection, late diagnosis, and uncertainties about its management are factors negatively impact their outcomes. We conducted a literature review searching reports on associated to HIV, cancer, maligned hemopathies, solid organ transplantation, immunotherapies, order check for peculiarities terms natural history challenges this population. HIV with usually had T CD4+ cell counts, pulmonary lymph nodes involvement, poorer prognosis (≈50% mortality). Most cancer carcinoma respiratory tract. Among was more often related lymphoma. In general, malignant diseases stage. transplant recipients phase kidney high mortality rate (44%). Despite being uncommon, reactivation latent may take place setting exhibiting particularities it carries higher rates than normal