A Diabetes-Related Dietary Pattern Is Associated with Incident Diabetes in Obese Men in the Korean Genome Epidemiology Study

摘要: BACKGROUND Diet plays an important role in both the development and management of diabetes. OBJECTIVE Using data from Korean Genome Epidemiology Study, we assessed dietary patterns associated with clinical indicators METHODS This study included 7255 subjects aged 40-69 y. Individuals chronic diseases were excluded. The daily intakes specific food items using a dish-based semiquantitative food-frequency questionnaire comprising 103 items; then grouped into 26 groups. Dietary analyzed by reduced rank regression method glycated hemoglobin, homeostasis model insulin resistance, fasting glucose concentrations as dependent variables. We investigated associations between incident diabetes Cox proportional hazards model. RESULTS During 11.5-y follow-up, incidence was 11.8/1000 person-years. pattern related to selected biomarkers characterized relatively high intake kimchi, beef, other meat, fish, coffee men rice, fruit women. In men, association significant only obese group, those top quartile score had 1.72 times (95% CI: 1.15, 2.56 times) greater risk than bottom quartile. Conversely, women not CONCLUSION regression, identified long-term follow-up Korea.