Outcomes of newborn infants with pulmonary hypertension treated with oral sildenafil in a tertiary care center in Amman, Jordan

摘要: Background: Persistent pulmonary hypertension of the newborn (PPHN) is a disease with high mortality rate. The incidence PPHN approximately 0.8 per 1,000 live births. Inhaled nitric oxide remains treatment choice, but in areas where inhaled not available, sildenafil citrate considered best alternative vasodilator. We conducted this study to investigate efficacy oral treating neonatal hypertension. Methods: This retrospective all newborns diagnosed who received over an 8-year period. Results: A total 27 were included study. most common primary was respiratory distress syndrome. rate 44.4%; cardiovascular shock at presentation died. Conclusions: Oral promising medication that can help neonates mild moderate hospital units available. Development protocol standardize care such infants will positively impact outcomes. Int J Clin Pediatr. 2019;8(2):27-31 doi: https://doi.org/10.14740/ijcp349