The occurrence and fate of tetracyclines in two pharmaceutical wastewater treatment plants of Northern China
作者： Jie Hou , Chong Wang , Daqing Mao , Yi Luo
DOI: 10.1007/S11356-015-5431-5
关键词:
摘要: Several parameters of the method, solid-phase extraction (SPE)-ultra-performance liquid chromatography (UPLC)-tandem mass spectrometry (MS/MS), were optimized to investigate presence and partitioning 18 antibiotics (including sulfonamides, tetracyclines, quinolones, macrolides, β-lactams) during various processing stages at two typical pharmaceutical wastewater treatment plants (PWWTPs) in northern China. Oxytetracycline (OTC), chlortetracycline (CTC), tetracycline (TC) all detected each stage both PWWTPs. Antibiotics largely removed through biological units PWWTPs, with removal efficiencies 62.0 78.3%. Mass balance analyses indicated that degradation (44.8-53.7% for PWWTP1 40.1-59.6% PWWTP2) was major mechanism responsible whereas contribution sorption by sludge (12.6-20.0% 18.7-33.5% less significant investigated pharmaceuticals. Although there tetracyclines large amounts still discharged effluent (up 32.0 ± 6.0 mg L(-1)) dewatered 5,481.1 ± 123.0 kg(-1)), which increased risk selecting antibiotic resistance receiving water soil environments.
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